Area of interest
Interconnection between immunity and metabolism in physiological conditions and in acute and chronic pathological settings (including cardiovascular, neurological, oncological, microbiological fields, etc.).
Objectives
Founder members
Humanitas Institute, Rozzano
His research focuses on immune–cancer–cardiovascular (CV) crosstalk, studying negative regulators of inflammation during chemotherapy, and investigating soluble innate humoral molecules as markers and mediators of tissue damage in infection and CVDs
francesco.scavello@humanitasresearch.it
Università di Padova
Immunometabolism and obesity-associated metabolic disorders
marina.debernard@unipd.it
Università di Pisa
Her work focuses on immunometabolic mechanisms driving immune responses in rheumatic diseases, integrating computational analysis, organoid models, and clinical data
valentina.pucino@unipi.it
IEOMI-CNR Napoli
She studies the interactions between the immune system and metabolism, with particular attention to the epigenetic aspects related to T lymphocyte metabolism in autoimmune diseases
claudia.larocca@cnr.it
IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) “Dino Amadori” S.r.l.
Hes research develops cellular immunotherapies for solid tumors by translating tumor microenvironment knowledge into therapeutic strategies.
marcella.tazzari@irst.emr.it
Sapienza Università di Roma
Regulatory T cells, tumor microenvironment, iron metabolism
silvia.piconese@uniroma1.it
Sapienza Università di Roma
Her research focuses on cancer immunology, with particular interest in immune–metabolic interactions regulating tissue homeostasis and cancer progression
alessandra.pinzongrimaldos@uniroma1.it
Sapienza Università di Roma
Study of platelet metabolism and platelet-immune crosstalk in cardiometabolic (MASLD, INOCA), autoimmune (systemic sclerosis) and haematological (ITP, ALL) disease
lucia.stefanini@uniroma1.it
CNR-IEOMI, Naples
She studies the interaction between the immune system and metabolism, focusing on regulatory T cells and extracellular vesicles, to understand how metabolic alterations affect the onset and progression of autoimmune diseases
giusy.derosa@unina.it
CNR-IEOMI, Naples
His work focuses on the connections between autophagy mechanisms and metabolism in key immune cells, with particular attention to conventional T lymphocytes (Tconvs) and regulatory T lymphocytes (Tregs).
gianmarcoesposito@cnr.it
Università degli Studi di Milano
His research activity is devoted to the investigation of molecular mechanisms involved in vascular and cardiometabolic diseases and their connection with immunometabolism from a translational perspective
Danilo.Norata@unimi.it
University if Ferrara
She investigates T cell metabolism and how factors such as aging and physical exercise modulate their metabolic and functional profile, shaping immune responses in different contexts, including vaccination, infection, and cancer
trrlne@unife.it
Università di Catanzaro
He studies Th17/Treg and purine/lactate metabolism in complex diseases
rosario.amato@unicz.it
Università degli studi di Napoli “Federico II”
She studies the interplay between metabolism and immune tolerance, focusing on regulatory T cells, anti-inflammatory proteins, and metabolic modulation in autoimmune diseases, including Multiple Sclerosis and Type 1 Diabetes.
alessandra.colamatteo@unina.it
University of Ferrara
His research activity focuses on T cell metabolic alterations in aging and chronic infections, using in vitro human cells and in vivo murine models to investigate the lipid metabolism and the associated functional responses
enrico.tassani@unife.it
Università di Ferrara
He has studied primary and secondary responses in cellular and murine models, with a particular focus on the phenotypic, immunometabolic, and functional characterization of lymphocytes under immunosenescent and non‑immunosenescent conditions
prtdvd@unife.it
IEOMI-CNR Napoli
Study of the interaction between metabolism and the immune system in physiological and pathological contexts
claudio.procaccini@cnr.it
Università di Milano
By combining expertise in lipid metabolism and immunity, she investigates the metabolic checkpoints that regulate cellular phenotype in order to identify new targets capable of limiting immune‑inflammatory activation in cardiometabolic diseases.
fabrizia.bonacina@unimi.it
University of Ferrara
Our research focuses on T cell metabolism, and in particular on the connection between immunometabolism and T cell functions in contexts of infections, vaccination, and ageing
nclfnc1@unife.it
University of Ferrara
Working in the field of viral immunology since 2020, investigating immune profiles and immune responses to viruses and vaccines in the context of physiological and accelerated senescence, with a strong focus on immunometabolic features
dllbrc@unife.it
Università di Perugia
She leads the Immunometabolism Lab, studying how amino acid metabolites, from immune cells and microbiota, also as cargo in extracellular vesicles, shape immune responses in autoimmunity, tumors, and in gene therapies
francesca.fallarino@unipg.it
Azienda Ospedaliera Universitaria Federico II
She studies the interplay between diet and immunometabolism, examining how metabolic pathways influenced by nutrients regulate immune self-tolerance and modulate regulatory T cell function in autoimmune conditions, including Multiple Sclerosis
claudia.russo989@gmail.com
Università di Perugia
His research explores how metabolism shapes dendritic cell function and immune responses in cancer
marco.gargaro@unipg.it
Universita’ di Verona
Main expertise in neutrophil biology, with a research focus on the phenotypic and molecular characterization of immunosuppressive neutrophil subpopulations
patrizia.scapini@univr.it
